FORPRION
BAVARIAN RESEARCH ASSOCIATION PRIONS
The association
In the wake of the first cases of BSE in Bavaria the Bavarian Government decided to take measures to fight prion diseases. At the beginning of the year 2001 a research initiative was begun, its result being the "Bayerischer Forschungsverbund Prionen". This research consortium is granted by the Ministry of Science, Research and Art and the Ministry of Health, Food and Consumer Protection.
Through basic and applied research the consortium aims to make progress in the diagnosis and therapy of human and animal prion diseases, as well as in the field of preventive consumer protection. The focuses are on the following:
- Basic research
- Pathogenesis of prion diseases
- Therapy
- Diagnosis
- Epidemiology and veterinary medicine
- Genetics of BSE
- Consumer protection
Network:
The research consortium is a network of 25 projects at six Bavarian universities and an Institute of the "Max-Planck-Society". The universities of Nürnberg-Erlangen, Würzburg, Bayreuth, Ludwig-Maximilians-Universität München, Technische Universität München and the Max-Planck-Institute of Biochemistry are members of FORPRION. FORPRION is also linked with the National German TSE Research Platform , the German CJD Surveillance and the <link http: www.neuropathologie.med.uni-muenchen.de neurobiobank_muenchen index.html _blank>Brain-Net, the German Reference Centre for Diseases of the CNS.
Organisation
Spokesperson
General Management
Managing-committee
Head of Research Division
- Dr. Ralf Alsfasser
- Prof. Dr. Johann Bauer
- Prof. Dr. Cord-Michael Becker
- Dr. Uwe Bertsch
- Prof. Dr. Thomas Brocker
- Prof. Dr. Volker Erfle
- Prof. Dr. Hans-Rudolf Fries
- Prof. Dr. Martin Förster
- Prof.Dr. Manfred Gareis
- Prof. Dr. Manfred Gerlach
- Dr. Armin Giese
- Dr. Martin Groschup
- Prof. Dr. Christian Haass
- Prof. Dr. Ulrich Hartl
- Prof. Dr. Jochen Herms
- Prof. Dr. Bertold Hock
- Prof. Dr. Wolfgang Klee
- Prof. Dr. Michael Klein
- Prof. Dr. Hans Kretzschmar
- Prof. Dr. Rudolf Martini
- Prof. Dr Ortwin Meyer
- Prof. Dr. Luis Moroder
- Prof. Dr. Erwin Märtlbauer
- Prof. Dr. Fritz G. Parak
- Prof. Dr. Monika Pischetsrieder
- Prof. Dr. Peter Riederer
- Prof. Dr. rer.nat. Siegfried Scherer
- Prof. Dr. Katrin Schiebel
- Prof. Dr. Wolfgang Schmahl
- Prof. Dr. Hermann M. Schätzl
- Prof. Dr. Michael Sendtner
- Prof. Dr. Andreas Stolle
- Prof. Dr. Jörg Tatzelt
- Prof. Dr. Paul Tavan
- Prof. Dr. Volker ter Meulen
- Prof. Dr. Uwe Truyen
- Prof. Dr. Rudi van Eldik
- Dr. Stefan Weiss
- Dr. Stefan Wiese
- Prof. Dr. Eckhard Wolf
Scientists
- Christian Bach
- Angela Bahlo
- T Düthorn
- Sabine Ebner
- Dipl.-Humanbiol. Alexa Ertmer
- Dr. Eckhard Flechsig
- Ulrike Frankenberg
- Dr. rer. nat. Holger Geue
- Dipl.Phys. Klaus Grantner
- Dr. Alex Greenwood
- Prof. Dr. Karl Heinritzi
- Judith Holtbecker
- PD Dr. rer. nat Andreas Humeny
- Dipl.Ing.agr.Univ Katrin Juling
- Dr. Xenia Kashkevich
- Dr. Regina Klose
- Igor Kobsar
- Priv.-Doz. Dr. Karl Kramer
- Prof. Dr. Christine Leib-Mösch
- O. Lipp
- Dr. Marko Maringer
- Dr. Ute Marx
- Dr. Ivica Medugorac
- Dipl.Phys. Matthias Mentler
- Prof. Dr. Franz Meußdorfer
- Prof. Dr. Karsten Meyer
- Mali Miyashita
- Dr. Simone Mueller
- Nicole Niklas
- Cindy Nitschke
- Anton Nowotni
- Dr. Birgit Oidtmann
- Dr. Rothraud Pichner
- Dr. Christian Renner
- Dr. Barbara Sandmeier
- Dipl. Biologin Christina Scherbel
- Dr. Christian Schörner
- Dr Martin Seifert
- Dr. Shneh Sethi
- Martina Stork
- Prof. Dr. Klaus Troeger
- Armgard Uehlhoff
- Dr.rer.nat. Carmen Villmann
- Jens Wagner
- Dr. Petra Weber
- Dipl. Biol. Stephan Weinhardt
- Andreas Weiss
- Dr. Heike Wendel
- Dr. Konstanze F. Winklhofer
- Dr.vetmed. Gerda Wuensch
- Dr. sc.hum. Seong-Wook Yun
- Achim Zahl
- Dr. Valeri Zakhartchenko
Partner
Scientific partner
- BFAV
- Institut für neue und neuartige Tierseuchenerreger
- Federal Research Centre for Nutrition and Food
- Institute for Microbiology and Toxicology
- FORPRION
- c/o LMU München, Zentrum für Neuropathologie und Prionforschung
- GSF
- Institute for Molecular Virology
- Julius-Maximilians-University Würzburg
- Institute for Virology und Immunbiology
- Klinik für Psychiatrie und Psychotherapie, Klinische Neurochemie
- Department of Neurology
- Department of Neurology (Neurobiology)
- University of Munich
- Fakultät für Physik, Sektion Physik
- II. Med. Tierklinik
- Institut für Biochemie
- Institut für Hygiene und Technologie der Lebensmittel tierischen Ursprungs
- Institut für Immunologie
- Institut für molekulare Tierzucht und Biotechnologie
- Institut für Tierpathologie
- Institut für Tierzucht
- Institut für Zoologie und Fischereibiologie
- Lehrstuhl für Hygiene und Technologie der Milch
- Lehrstuhl für Krankheiten des Schweines
- Lehrstuhl für Stoffwechselbiochemie
- Zentrum für Neuropathologie und Prionforschung
- Max-Planck-Institute
- TU Munich
- Center of Life Sciences
- Institute of Virology
- Institut für Mikrobiologie, Forschungszentrum für Milch und Lebensmittel Weihenstephan
- Institut für Molekulare Virologie
- Lehrstuhl für Tierhygiene
- Lehrstuhl für Tierzucht
- Physik Department E17
- Universität Bayreuth
- Lehrstuhl für Mikrobiologie
- Lehrstuhl für Struktur und Chemie der Biopolymere
- University of Erlangen
- Institut für Anorganische Chemie
- Institute for Biochemestry
- Institut für Pharmazie und Lebensmittelchemie
- Zentralinstitut für Tiergesundheit, Bayern
Partner of the industry
- Cenas AG
Projects
- Diagnosis of prion diseases
-
Epidemiology and Veterinary medicine
- Bay 1 Occurence of TSE in natural habitats: Transmission of prions through wild animals and farmed wild ruminants in Northern Bavaria
- LMU 13 Studies the genetic diversity of the porcine prion protein
- LMU 19 Clinical and Epidemiological Investigations of BSE in Bavaria
- LMU 19 a Occurrence and Stability of the BSE Agent in Foodstuff (primarily in Milk and Milk Products) and in the Environment
- LMU 21 Investigation of Sporadically Occurring Spongiform Brain Lesions in Cattle
- Genetics
-
Basic research on prion diseases
- Erl 8 Metal Ion Induced Conformational Changes in Peptides: A Putative Mechanism for the Formation of Abnormal Prion Protein Isoforms
- LMU 2 Cu(II)-binding of PrPC: Influence on Structure, Conformational Dynamics and Infectivity
- LMU 6 In Vivo Phosphorylation and Cellular Transport of Mutant and WT Prion Proteins in Living Neurons
- LMU 9 Phenotyping of Prion Diseases using GFP-PrP Chimeras in Transgenic Mice
- LMU 5 Analysis of Bovine and Human Prions in Cell Culture Systems for Diagnostic, Analytical and Therapeutic Purposes
- Therapy of prion diseases
-
Pathogenesis of prion diseases
- LMU 11 Function of Dendritic Cells (DC) in the Pathogenesis of Prion Disease
- TUM 7 The Role of Activated Retroviral Genes as Cofactors in Prion-induced Spongiform Encephalopathy: Studies with a Mouse Model for Pathogenesis and Therapy
- Wü 1 Pathogenesis of Prion Diseases I
- Wü 1 Pathogenesis of Prion Diseases II
- Wü 1 Pathogenesis of Prion Diseases III
- Wü 1 Pathogenesis of Prion Diseases IV
-
Consumer protection
- Erl 3 High Sensitive Immunassay for Detection of Central Nervous Tissue in Food
- LMU 19 a Occurrence and Stability of the BSE Agent in Foodstuff (primarily in Milk and Milk Products) and in the Environment
- LMU 20 Species specific detection of central nervous tissue or other TSE risk material in meat products
- TUM 12 Natural Isotope Ratio of Bioelements as an Indicator of the Origin of Animal Products and of Animal Protein in Ruminant Feed
Contact
Dr. Rosi Lederer
Universität Regensburg
Klinik und Poliklinik für Neurologie am Bezirksklinikum Regensburg
Universitätsstr. 84
93053 Regensburg
Telefon: +49-89-2180 75258
Email: forneurocell@klinik.uni-regensburg.de