FOR-COVID

Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

Dennis Lapuente, Jana Fuchs, Jonas Willar, Ana Vieira Antão, Valentina Eberlein, Nadja Uhlig, Leila Issmail , Anna Schmidt, Friederike Oltmanns, Antonia Sophia Peter, Sandra Mueller-Schmucker, Pascal Irrgang, Kirsten Fraedrich, Andrea Cara, Markus Hoffmann, Stefan Pöhlmann, Armin Ensser, Cordula Pertl, Torsten Willert, Christian Thirion, Thomas Grunwald, Klaus Überla, Matthias Tenbusch

Nat Commun. 2021 Nov 26;12(1):6871. 

doi: 10.1038/s41467-021-27063-4

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626513/

Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination

Pascal Irrgang, Juliane Gerling, Katharina Kocher, Dennis Lapuente, Philipp Steininger,Katharina Habenicht, Monika Wytopil, Stephanie Beileke, Simon Schäfer, Jahn Zhong, George Ssebyatika, Thomas Krey, Valeria Falcone, Christine Schülein, Antonia Sophia Peter, Krystelle Nganou-Makamdop, Hartmut Hengel, Jürgen Held, Christian Bogdan, Klaus Überla, Kilian Schober, Thomas H. Winkler, Matthias Tenbusch

Full Text

Science Immunology 2023, 8(79):eade2798. PMID: 36548397

https://www.science.org/doi/epdf/10.1126/sciimmunol.ade2798

Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2

Emmanuel Vogel, Katharina Kocher, Alina Priller, Cho-Chin Cheng, Philipp Steininger, Bu-Hung Liao, Nina Körber, Annika Willmann, Pascal Irrgang, Jürgen Held, Carolin Moosmann, Viviane Schmidt, Stephanie Beileke, Monika Wytopil, Sarah Heringer, Tanja Bauer, Ronja Brockhoff, Samuel Jeske, Hrvoje Mijocevic, Catharina Christa, Jon Salmanton-García, Kathrin  Tinnefeld, Christian Bogdan, Sarah Yazici, Percy Knolle, Oliver A Cornely, Klaus Überla, Ulrike Protzer, Kilian Schober, Matthias Tenbusch

Full Text

EBioMedicine. 2022 Nov; 85: 104294 PMID: 36206622

https://pubmed.ncbi.nlm.nih.gov/36206622/

Comparative Immunogenicity of COVID-19 Vaccines in a Population-Based Cohort Study with SARS-CoV-2-Infected and Uninfected Participants

David Peterhoff, Sebastian Einhauser, Stephanie Beileke, Hans-Helmut Niller, Felix Günther,
Michael Schachtner, Benedikt Asbach, Philipp Steininger, Matthias Tenbusch, Antonia S. Peter,
Andre Gessner, Ralph Burkhardt Iris M. Heid, Ralf Wagner, and Klaus Überla

Full Text

Vaccines (Basel). 2022 Feb 18;10(2):324. PMID: 35214782

https://www.mdpi.com/2076-393X/10/2/324

Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.

Paul R. Wratil, Marcel Stern, Alina Priller, Annika Willmann, Giovanni Almanzar, Emanuel Vogel, Martin Feuerherd, Cho-Chin Cheng, Sarah Yazici, Catharina Christa, Samuel Jeske, Gaia Lupoli, Tim Vogt, Manuel Albanese, Ernesto Mejias-Perez, Stefan Bauernfried, Natalia Graf, Hrvoje Mijocevic, Martin Vu, Kathrin Tinnefeld, Jochen Wettengel, Dieter Hoffmann, Maximilian Münchhoff, Christopher Daechert, Helga Mairhofer, Stefan Krebs, Volker Fingerle, Alexander Graf, Philipp Steininger, Helmut Blum, Veit Hornung, Bernhard Liebl, Klaus Überla, Martina Prelog, Percy Knolle, Oliver T. Keppler & Ulrike Protzer

Full Text

Nature Medicine 2022, 28:496-503. PMID: 35090165

https://www.nature.com/articles/s41591-022-01715-4

Higher Infection Risk among Health Care Workers and Lower Risk among Smokers Persistent across SARS-CoV-2 Waves-Longitudinal Results from the Population-Based TiKoCo Seroprevalence Study

Felix Günther, Sebastian Einhauser, David Peterhoff, Simon Wiegrebe, Hans Helmut Niller,
Stephanie Beileke, Philipp Steininger, Ralph Burkhardt, Helmut Küchenhoff, Olaf Gefeller,
Klaus Überla, Iris M. Heid and Ralf Wagner

Full Text

Int J Environ Res Public Health. 2022 Dec 17;19(24):16996. PMID: 36554876

https://www.mdpi.com/1660-4601/19/24/16996

Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County-Results from a Population-Based Longitudinal Study in Germany

Sebastian Einhauser, David Peterhoff, Stephanie Beileke, Felix Günther, Hans-Helmut Niller,
Philipp Steininger, Antje Knöll, Klaus Korn, Melanie Berr, Anja Schütz, Simon Wiegrebe,
Klaus J. Stark, André Gessner, Ralph Burkhardt, Michael Kabesch, Holger Schedl,
Helmut Küchenhoff, Annette B. Pfahlberg, Iris M. Heid, Olaf Gefeller,
Klaus Überla and Ralf Wagner

Full Text

Viruses. 2022 May 27;14(6):1168. PMID: 35746640

https://www.mdpi.com/1999-4915/14/6/1168

B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity

Dennis Lapuente, Thomas H. Winkler, Matthias Tenbusch

Full Text

Review Article

Cell Mol Immunol 2024. 21:144-158. PMID: 37945737

https://doi.org/10.1038/s41423-023-01095-w

Population-based study of the durability of humoral immunity after SARS-CoV-2 infection

David Peterhoff, Simon Wiegrebe, Sebastian Einhauser, Arisha J. Patt, Stephanie Beileke, Felix Günther, Philipp Steininger, Hans H. Niller, Ralph Burkhardt, Helmut Küchenhoff, Olaf Gefeller, Klaus Überla, Iris M. Heid, Ralf Wagner

Full Text

Front Immunol 2023. 14:1242536. PMID: 37868969

DOI: 10.3389/fimmu.2023.1242536

Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020

Wagner R, Peterhoff D, Beileke S, Günther F, Berr M, Einhauser S, Schütz A, Niller HH, Steininger P, Knöll A, Tenbusch M, Maier C, Korn K, Stark KJ, Gessner A, Burkhardt R, Kabesch M, Schedl H, Küchenhoff H, Pfahlberg AB, Heid IM, Gefeller O, Überla K.
 

Full text

Viruses. 2021 Jun 10;13(6):1118. doi: 10.3390/v13061118

Spectrum Bias and Individual Strengths of SARS-CoV-2 Serological Tests—A Population-Based Evaluation

Sebastian Einhauser, David Peterhoff, Hans Helmut Niller, Stephanie Beileke, Felix Günther, Philipp Steininger, Ralph Burkhardt, Iris M. Heid, Annette B. Pfahlberg, Klaus Überla, Olaf Gefeller, Ralf Wagner

Full text

Diagnostics (Basel) 2021 11(10):1843. PMID: 34679541

DOI: 10.3390/diagnostics11101843