FOR-COVID

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

Alexey Stukalov, Virginie Girault^, Vincent Grass, Ozge Karayel, Valter Bergant,
Christian Urban, Darya A. Haas, Yiqi Huang, Lila Oubraham, Anqi Wang,
M. Sabri Hamad, Antonio Piras, Fynn M. Hansen, Maria C. Tanzer, Igor Paron,
Luca Zinzula, Thomas Engleitner, Maria Reinecke, Teresa M. Lavacca, Rosina Ehmann,
Roman Wölfel, Jörg Jores, Bernhard Kuster, Ulrike Protzer, Roland Rad,
John Ziebuhr, Volker Thiel, Pietro Scaturro, Matthias Mann & Andreas Pichlmair ✉

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Nature​​​​​​ 2021 Jun;594(7862):246-252.

doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12.

Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases

Valter Bergant, Shintaro Yamada, Vincent Grass, Yuta Tsukamoto, Teresa Lavacca, Karsten Krey, Maria-Teresa Mühlhofer, Sabine Wittmann, Armin Ensser, Alexandra Herrmann, Anja vom Hemdt, Yuriko Tomita, Shutoku Matsuyama, Takatsugu Hirokawa, Yiqi Huang, Antonio Piras, Constanze A Jakwerth, Madlen Oelsner, Susanne Thieme, Alexander Graf, Stefan Krebs, Helmut Blum, Beate M Kümmerer, Alexey Stukalov,Carsten B Schmidt-Weber, Manabu Igarashi, Thomas Gramberg, Andreas Pichlmair, and Hiroki Kato

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EMBO J. 2022 Sep 1;41(17):e111608

DOI: 10.15252/embj.2022111608

ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion

Georg Jocher, Vincent Grass, Sarah K Tschirner, Lydia Riepler, Stephan Breimann,Tugberk Kaya, Madlen Oelsner, M Sabri Hamad, Laura I Hofmann, Carl P Blobel,Carsten B Schmidt-Weber, Ozgun Gokce, Constanze A Jakwerth, Jakob Trimpert, Janine Kimpel, Andreas Pichlmair, and Stefan F Lichtenthaler

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EMBO Rep. 2022 Jun 7;23(6):e54305

https://www.embopress.org/doi/full/10.15252/embr.202154305

Recruitment of highly cytotoxic CD8+T cell receptors in mild SARS-CoV-2 infection

Karolin I. Wagner, Laura M. Mateyka, Sebastian Jarosch, Vincent Grass, Simone Weber, Kilian Schober, Monika Hammel, Teresa Burrell, Behnam Kalali, Holger Poppert, Henriette Beyer, Sophia Schambeck, Stefan Holdenrieder,  Andrea Strötges-Achatz, Verena Haselmann, Michael Neumaier, Johanna Erber, Alina Priller,
Sarah Yazici, Hedwig Roggendorf, Marcus Odendahl, Torsten Tonn, Andrea Dick, Klaus Witter, Hrvoje Mijocevic, Ulrike Protzer, Percy A. Knolle, Andreas Pichlmair, Claudia S. Crowell, Markus Gerhard, Elvira D’Ippolito, and Dirk H. Busch

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Cell Rep. 2022 Jan 11;38(2):110214. PMID: 34968416

https://doi.org/10.1016/j.celrep.2021.110214

SARS-CoV-2 CD8+ T cell killing assays using replicating viruses and transgenic antigens

Laura M. Mateyka, Vincent Grass, Andreas Pichlmair, Dirk H. Busch, and Elvira D’Ippolito

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STAR Protoc. 2022 Dec 16;3(4):101699. PMID: 36152303

https://www.sciencedirect.com/science/article/pii/S2666166722005792

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

Nora Schmidt, Sabina Ganskih, Yuanjie Wei, Alexander Gabel, Sebastian Zielinski, Hasmik Keshishian, Caleb A Lareau, Liv Zimmermann, Jana Makroczyova, Cadence Pearce, Karsten Krey, Thomas Hennig, Sebastian Stegmaier, Lambert Moyon, Marc Horlacher, Simone Werner, Jens Aydin, Marco Olguin-Nava, Ramya Potabattula, Anuja Kibe, Lars Dölken, Redmond P Smyth, Neva Caliskan, Annalisa Marsico, Christine Krempl, Jochen Bodem, Andreas Pichlmair, Steven A Carr, Petr Chlanda, Florian Erhard, Mathias Munschauer

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Cell. 2023 Sep 28:S0092-8674(23)00980-7.

doi: 10.1016/j.cell.2023.09.002.

https://doi.org/10.1016/j.cell.2023.09.002

MDM2 Influences ACE2 Stability and SARS-CoV-2 Uptake

Quirin Emslander, Karsten Krey, Sabri Hamad, Susanne Maidl, Lila Oubraham, Joshua Hesse, Alexander Henrici, Katharina Austen, Julia Mergner, Vincent Grass, Andreas Pichlmair

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Viruses 2023, 15:1763. PMID: 37632105;

https://doi.org/10.3390/v15081763