FOR-COVID

Comparison of four commercial, automated antigen tests to detect SARS‑CoV‑2 variants of concern

Andreas Osterman, Maximilian Iglhaut, Andreas Lehner,  Patricia Spaeth, Marcel Stern,
Hanna Autenrieth, Maximilian Muenchhoff,  Alexander Graf,  Stefan Krebs,  Helmut Blum, 
Armin Baiker, Natascha Grzimek-Koschewa, Ulrike Protzer,  Lars Kaderali, Hanna-Mari Baldauf, Oliver T. Keppler

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Med Microbiol Immunol. 2021 Dec;210(5-6):263-275.

doi: 10.1007/s00430-021-00719-0.

PMID: 34415422

https://link.springer.com/article/10.1007/s00430-021-00719-0

Longitudinal SARS-CoV-2 neutralization of Omicron BA. 1, BA. 5 and BQ. 1.1 after four vaccinations and the impact of break-through infections in hemodialysis patients

Louise Platen, Bo-Hung Liao, Myriam Tellenbach, Cho-Chin Cheng, Christopher Holzmann-Littig, Catharina Christa, Christopher Dächert, Verena Kappler, Romina Bester, Maia Lucia Werz, Emely Schönhals, Eva Platen, Peter Eggerer, Laëtitia Tréguer , Claudius Küchle, Christoph Schmaderer, Uwe Heemann, Oliver T. Keppler, Lutz Renders, Matthias Christoph Braunisch, and Ulrike Protzer

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Clin Kidney J. 2023, 16(12):2447-2460. PMID: 38046025;

DOI: 10.1093/ckj/sfad147

Comparable cellular and humoral immunity upon homologous and heterologous COVID-19 vaccination regimens in kidney transplant recipients

Nina Körber, Christopher Holzmann-Littig, Gesa Wilkens, Bo-Hung Liao, Maia L. Werz, Louise Platen,
Cho-Chin Cheng, Myriam Tellenbach, Verena Kappler, Viktor Lehner, Hrvoje Mijocevic, Catharina Christa, Volker Assfalg, Uwe Heemann, Christoph Schmaderer, Ulrike Protzer, Matthias C. Braunisch, Tanja Bauer and Lutz Renders

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Front Immunol. 2023 Mar 31;14:1172477. PMID: 37063863

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172477/full

Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma

Andrea Keppler-Hafkemeyer, Christine Greil, Paul R. Wratil, Khalid Shoumariyeh, Marcel Stern, Annika Hafkemeyer, Driti Ashok, Alexandra Hollaus, Gaia Lupoli, Alina Priller, Marie L. Bischof, Gabriele Ihorst, Monika Engelhardt, Reinhard Marks, Jürgen Finke, Hannah Bertrand, Christopher Dächert, Maximilian Muenchhoff, Irina Badell, Florian Emmerich, Hridi Halder, Patricia M. Spaeth, Percy A. Knolle, Ulrike Protzer, Michael von Bergwelt-Baildon, Justus Duyster, Tanja N. Hartmann, Andreas Moosmann and Oliver T. Keppler

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Nature Cancer 2022, 4(1): 85-91. PMID: 36543907

https://doi.org/10.1038/s43018-022-00502-x

Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2

Emmanuel Vogel, Katharina Kocher, Alina Priller, Cho-Chin Cheng, Philipp Steininger, Bu-Hung Liao, Nina Körber, Annika Willmann, Pascal Irrgang, Jürgen Held, Carolin Moosmann, Viviane Schmidt, Stephanie Beileke, Monika Wytopil, Sarah Heringer, Tanja Bauer, Ronja Brockhoff, Samuel Jeske, Hrvoje Mijocevic, Catharina Christa, Jon Salmanton-García, Kathrin  Tinnefeld, Christian Bogdan, Sarah Yazici, Percy Knolle, Oliver A Cornely, Klaus Überla, Ulrike Protzer, Kilian Schober, Matthias Tenbusch

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EBioMedicine. 2022 Nov; 85: 104294 PMID: 36206622

https://pubmed.ncbi.nlm.nih.gov/36206622/

Improved SARS-CoV-2 Neutralization of Delta and Omicron BA.1 Variants of Concern after Fourth Vaccination in Hemodialysis Patients

Cho-Chin Cheng, Louise Platen, Catharina Christa, Myriam Tellenbach, Verena Kappler,
Romina Bester, Bo-Hung Liao, Christopher Holzmann-Littig, Maia Werz, Emely Schönhals, Eva Platen,
Peter Eggerer, Laëtitia Tréguer, Claudius Küchle, Christoph Schmaderer, Uwe Heemann, Lutz Renders, Ulrike Protzer and Matthias Christoph Braunisch

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Vaccines (Basel). 2022 Aug 16;10(8):1328. PMID: 36016216

https://www.mdpi.com/2076-393X/10/8/1328

Recruitment of highly cytotoxic CD8+T cell receptors in mild SARS-CoV-2 infection

Karolin I. Wagner, Laura M. Mateyka, Sebastian Jarosch, Vincent Grass, Simone Weber, Kilian Schober, Monika Hammel, Teresa Burrell, Behnam Kalali, Holger Poppert, Henriette Beyer, Sophia Schambeck, Stefan Holdenrieder,  Andrea Strötges-Achatz, Verena Haselmann, Michael Neumaier, Johanna Erber, Alina Priller,
Sarah Yazici, Hedwig Roggendorf, Marcus Odendahl, Torsten Tonn, Andrea Dick, Klaus Witter, Hrvoje Mijocevic, Ulrike Protzer, Percy A. Knolle, Andreas Pichlmair, Claudia S. Crowell, Markus Gerhard, Elvira D’Ippolito, and Dirk H. Busch

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Cell Rep. 2022 Jan 11;38(2):110214. PMID: 34968416

https://doi.org/10.1016/j.celrep.2021.110214

Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.

Paul R. Wratil, Marcel Stern, Alina Priller, Annika Willmann, Giovanni Almanzar, Emanuel Vogel, Martin Feuerherd, Cho-Chin Cheng, Sarah Yazici, Catharina Christa, Samuel Jeske, Gaia Lupoli, Tim Vogt, Manuel Albanese, Ernesto Mejias-Perez, Stefan Bauernfried, Natalia Graf, Hrvoje Mijocevic, Martin Vu, Kathrin Tinnefeld, Jochen Wettengel, Dieter Hoffmann, Maximilian Münchhoff, Christopher Daechert, Helga Mairhofer, Stefan Krebs, Volker Fingerle, Alexander Graf, Philipp Steininger, Helmut Blum, Veit Hornung, Bernhard Liebl, Klaus Überla, Martina Prelog, Percy Knolle, Oliver T. Keppler & Ulrike Protzer

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Nature Medicine 2022, 28:496-503. PMID: 35090165

https://www.nature.com/articles/s41591-022-01715-4

Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany

Johanna Erber, Verena Kappler, Bernhard Haller, Hrvoje Mijočević, Ana Galhoz, Clarissa Prazeres da Costa, Friedemann Gebhardt, Natalia Graf, Dieter Hoffmann, Markus Thaler, Elke Lorenz, Hedwig Roggendorf, Florian Kohlmayer, Andreas Henkel, Michael P. Menden, Jürgen Ruland, Christoph D. Spinner, Ulrike Protzer, Percy Knolle, Paul Lingor

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Emerg Infect Dis. 2022 Mar;28(3):572-581. PMID: 35195515

https://wwwnc.cdc.gov/eid/article/28/3/20-4436_article

Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents.

Nina Koerber, Alina Priller, Sarah Yazici, Tanja Bauer, Cho-Chin Cheng, Hrvoje Mijočević, Hannah Wintersteller, Samuel Jeske, Emanuel Vogel, Martin Feuerherd, Kathrin Tinnefeld, Christof Winter, Jürgen Ruland, Markus Gerhard, Bernhard Haller, Catharina Christa, Otto Zelger, Hedwig Roggendorf, Martin Halle, Johanna Erber, Paul Lingor, Oliver Keppler, Dietmar Zehn, Ulrike Protzer & Percy A. Knolle

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Nature Communications 2022, 13(1):153. PMID: 35013191

https://www.nature.com/articles/s41467-021-27649-y

Viral genome sequencing to decipher in‑hospital SARS‑CoV‑2 transmission events

Elisabeth Esser, Eva C. Schulte, Alexander Graf, Alexander Karollus, Nicholas H. Smith, Thomas Michler, Stefan Dvoretskii, Angel Angelov, Michael Sonnabend, Silke Peter, Christina Engesser, Aleksandar Radonic, Andrea Thürmer, Max von Kleist, Friedemann Gebhardt, Clarissa Prazeres da Costa, Dirk H. Busch, Maximilian Muenchhoff, Helmut Blum, Oliver T. Keppler, Julien Gagneur, Ulrike Protzer

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Sci Rep 2024 14:5768. PMID: 39459123

https://doi.org/10.1038/s41598-024-56162-7

Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages

Andreas Osterman, Franziska Krenn, Maximilian Iglhaut, Irina Badell, Andreas Lehner, Patricia M. Späth, Marcel Stern, Hanna Both, Sabine Bender, Maximilian Muenchhoff, Alexander Graf, Stefan Krebs, Helmut Blum, Timo Grimmer, Jürgen Durner, Ludwig Czibere, Christopher Dächert, Natascha Grzimek‑Koschewa, Ulrike Protzer, Lars Kaderali, Hanna‑Mari Baldauf, Oliver T. Keppler

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Med Microbiol Immunol 2023 212(5):307-322. PMID: 37561226.

https://doi.org/10.1007/s00430-023-00774-9

Immunogenicity of a silica nanoparticle-based SARS-CoV-2 vaccine in mice

Clara Barbey, Jinpeng Su, Martina Billmeier, Nadine Stefan, Romina Bester,
George Carnell, Nigel Temperton, Jonathan Heeney, Ulrike Protzer, Miriam Breunig,
Ralf Wagner, David Peterhoff

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Eur J Pharmaceut Biopharmaceut 2023 192:41-55. PMID: 37774890,

DOI: 10.1016/j.ejpb.2023.09.015

T-Cell-Dominated Immune Response Resolves Protracted SARS-CoV-2 Infection in the Absence of Neutralizing Antibodies in an Immunocompromised Individual

Till Bunse, Nina Koerber, Hannah Wintersteller, Jochen Schneider, Alexander Graf, Aleksandar Radonic, Andrea Thuermer, Max von Kleist, Helmut Blum, Christoph D. Spinner, Tanja Bauer, Percy A. Knolle, Ulrike Protzer, Eva C. Schulte

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Microorganisms 2023 11(6):1562. PMID: 37375064

DOI: 10.3390/microorganisms11061562

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

Alexey Stukalov, Virginie Girault^, Vincent Grass, Ozge Karayel, Valter Bergant,
Christian Urban, Darya A. Haas, Yiqi Huang, Lila Oubraham, Anqi Wang,
M. Sabri Hamad, Antonio Piras, Fynn M. Hansen, Maria C. Tanzer, Igor Paron,
Luca Zinzula, Thomas Engleitner, Maria Reinecke, Teresa M. Lavacca, Rosina Ehmann,
Roman Wölfel, Jörg Jores, Bernhard Kuster, Ulrike Protzer, Roland Rad,
John Ziebuhr, Volker Thiel, Pietro Scaturro, Matthias Mann & Andreas Pichlmair ✉

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Nature​​​​​​ 2021 Jun;594(7862):246-252.

doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12.