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VA-6 Bacteria and cancer Cancer diseases are more and more frequent, the main reason being the increasing life expectancy. Furthermore, the detection of some cancers was first made possible by the…

VA-5 Reverse vaccinology against chlamydial infections Chlamydia are bacteria, which need to invade host cells for their replication, i.e. they grow within cells and are therefore less accessible…

VA-4 Genome-based vaccine strategies against HIV Despite of excessive financial and scientific efforts, there is still no control of the HIV pandemic. Up to date, the development of effective…

VA-2 Development of a therapeutic T-cell vaccine against Hepatitis C Virus (HCV) The chronic infection with Hepatitis C Virus (HCV), which is a RNA virus belonging to the family of flaviviruses,…

DT-8 HIV-1 Vpr as a target for antiviral therapy Since the beginning of the 1980s millions of people have been infected with human immunodeficiency virus type 1 (HIV-1), the causative agent of the…

DT-6 Antibiotic resistance of Pseudomonas aeruginosa from Cystic Fibrosis patients Cystic fibrosis (CF) is the most common autosomal recessive disease in the Caucasian population arising from…

DT-5 Development of a Microsphere based multiplex serology for differential diagnosis in reactive arthritis and lyme arthritis. Bacterial infections can cause apart from their typical acute, febrile…

DT-4 Genome-based identification of targets specific for bovine Staphylococcus aureus isolates Staphylococcus aureus is one of the most important causes of bovine mastitis causing significant health…

DT-3 H. pylori pathodiagnostics Epidemiological data suggest that the bacterial pathogen Helicobacter pylori infects about 20 Mio. German citizens. Infection is mostly asymptomatic, but 10-15% of…

DT-1 Improvement of a DNA array for diagnostics of clinically relevant enterobacteria Enterobacteria comprise a variety of non-pathogenic, commensal variants, which belong to the normal gut flora of…